What it is
Pinealon is a tripeptide bioregulator with the sequence Glu-Asp-Arg (EDR). Pantheon's source article frames it for brain and nervous-system research, including cognitive clarity, oxidative stress, circadian support, and neuroprotection.
Mechanism of action
Pinealon has been studied for antioxidant and gene-expression effects. Cell and animal work suggests reduced reactive oxygen species accumulation and possible interactions with DNA regions related to antioxidant defense, neuronal differentiation, apoptosis regulation, and synaptic plasticity.
Evidence summary
Evidence comes mainly from cell, animal, and bioregulator literature. It should be treated as an educational research compound with limited Western human clinical data.
Pantheon dosing guide
- Application
- Subcutaneous injection.
- BAC Water
- 2 ml
- Dose
- 500 mcg to 1 mg (10 to 20 units)
- Frequency & Cycle Length
- Daily for 10 to 20 days. Repeat 1-3 times yearly as needed.
- Timing
- Morning or early afternoon.
- Key Benefits
- Supports brain and nervous-system health. Supports cognitive clarity. Supports circadian rhythm and sleep quality. Promotes neuroprotective antioxidant activity.
Additional research protocol context
The printed guide above is Pantheon's dosing reference. These broader research examples are provided as context and may use different schedules.
- 10 mg vial reconstituted with 2.0 ml bacteriostatic water
- 500 mcg-1 mg subcutaneous daily
- 10-20 day courses, repeated 1-3 times yearly as needed
Side effects & safety
- Injection-site redness, tenderness, itching, or mild swelling
- Headache, fatigue, lightheadedness, mild nausea, or temporary sleep changes
- Mood changes, irritability, or restlessness may occur in sensitive individuals
Cited studies
- Kozina LS, et al. (2011). Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes. Rejuvenation Research.PMID 21978084Read source ↗
- (2020). EDR Peptide: possible mechanism of gene expression and protein synthesis regulation in Alzheimer's disease. Molecules.Read source ↗
- (2021). Neuroprotective effects of tripeptides--epigenetic regulators in a mouse model of Alzheimer's disease. Pharmaceuticals.Read source ↗
- Khavinson V, et al. (2021). Peptide Regulation of Gene Expression: A Systematic Review. Molecules.Read source ↗
All content is for research and educational purposes. Peptides described are sold for laboratory research use only and are not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare professional before beginning any protocol.