SS-31 — Reference, Dosing & Cited Studies

What it is

SS-31, also known as elamipretide or MTP-131, concentrates near the inner mitochondrial membrane and is researched for cellular energy, mitochondrial stress, exercise tolerance, and healthy-aging protocols.

Mechanism of action

SS-31 binds cardiolipin, a phospholipid that helps organize the inner mitochondrial membrane and electron transport chain. Stabilizing cardiolipin-dependent structure may support ATP production and reduce mitochondrial reactive oxygen species.

Evidence summary

Elamipretide has clinical research in primary mitochondrial myopathy and an FDA-approved prescription form for Barth syndrome. Pantheon customer-facing protocols should still be treated as educational and clinician-guided.

Pantheon dosing guide

Application: Subcutaneous injection.
BAC Water: 10 mg: 2 ml 40 mg: 2 ml
Dose: 10 mg: 40-100 units (2-5 mg) 40 mg: 10-25 units (2-5 mg)
Frequency & Cycle Length: 5 days on / 2 days off. 4 to 8 weeks.
Timing: Morning most common. Pre-workout if applicable.
Key Benefits: Supports mitochondrial function. Protects cardiolipin and cellular energy production. Supports endurance and exercise tolerance. Helps reduce oxidative stress.

Additional research protocol context

The printed guide above is Pantheon's dosing reference. These broader research examples are provided as context and may use different schedules.

10 mg vial: 2.0 ml BAC water; 40-100 units delivers 2-5 mg
40 mg vial: 2.0 ml BAC water; 10-25 units delivers 2-5 mg
5 days on / 2 days off for 4-8 weeks; morning or pre-workout timing is common

Side effects & safety

Injection-site redness, stinging, tenderness, itching, or mild swelling
Headache, nausea, dizziness, lightheadedness, or temporary fatigue
Rare allergic or cardiovascular symptoms should be treated as stop-and-seek-care signals

Cited studies

Disclaimer

All content is for research and educational purposes. Peptides described are sold for laboratory research use only and are not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare professional before beginning any protocol.