Prime Metabolic: 12-Week Cycle

Why People Choose The Prime Metabolic 12-Week Cycle

• Promotes
  meaningful, sustained weight loss with appetite control (triple-agonist activity)
• Improves blood sugar control and insulin sensitivity to support healthier glucose dynamics
• Supports cellular energy and metabolic efficiency via NNMT inhibition (pairs well with weight-loss stacks)
• Accelerates soft-tissue healing and recovery (tendon, ligament, and muscle) while reducing inflammation
• Repairs and protects the gut lining to support GI comfort and resilience
• Enhances joint mobility and flexibility to keep you moving during training and recovery
• Supports healthy blood flow and angiogenesis in healing tissues for better repair
• Contributes to overall cardio-metabolic health alongside lifestyle changes
• Synergistic stack for “repair while you cut”—pairing tissue regeneration with fat-loss support
• Resets metabolic balance for sustainable fat-loss and recovery — the core promise of Prime Metabolic Reset

What’s In Your Prime Metabolic 12-Week Cycle Kit

Peptides

• 2 × Retatrutide (10 mg)
• 4 × BPC-157 (5 mg)
• 4 × TB-500 (5 mg)
• 3 × 5-Amino-1MQ (5 mg)

Supplies

• 4 × 10 mL Bacteriostatic Water (BAC Water)
• 75 × 1 mL insulin syringes (30–31G, 6–8 mm)
• 14 × 3 mL reconstitution syringes
• 14 × syringe tips (vial vents)
• 100 × alcohol pads
• Step-by-step dosing protocol.

Peptide Storage

Storage for Lyophilized (Freeze-Dried) Peptides: (Powder Form)

• After arrival: Store dry/lyophilized vials in the refrigerator (2 to 8 °C) for up to 6 months, or in the freezer (−20 °C or colder) for up to 2 years. Avoid repeated freezing and thawing.
• Keep vials tightly capped, dry, dark, and protected from moisture.
• Avoid repeated freezing and thawing

Storage for Reconstituted Peptides: (Mixed with BAC Water)

• Refrigerate 2 to 8 °C
• Do not freeze
• Use within 45 days unless the product label/protocol says otherwise.
• Label vials with date and concentration

Reconstitution (Mixing)

For easy calculating and to fit the full 12-week cycle:

• Retatrutide 10 mg: Add 2.0 mL BAC Water
• BPC-157 5 mg: Add 2.5 mL BAC Water
• TB-500 5 mg: Add 2.5 mL BAC Water
• 5-Amino-1MQ 5 mg: Add 3.0 mL BAC Water

Gently swirl or roll after adding BAC Water—do not shake.

Injection (Dosing)

Timing: Inject once each morning on an empty stomach at least 30 minutes before food.

Frequency

• Take daily peptides (BPC-157, TB-500, 5-Amino-1MQ) Monday to Friday.
• Weekends off for BPC-157, TB-500, and 5-Amino-1MQ (5 days on / 2 days off).
• Retatrutide is once weekly on your chosen day (keep the same day/time each week).

Injection Method: Subcutaneous (SQ)

Syringe: Insulin type (1 mL, 30–31G, 6–8 mm)

Combine in the same syringe Monday to Friday
(Draw from each vial into one syringe):

• BPC-157: 15 units (300 mcg)
• TB-500: 15 units (300 mcg)
• 5-Amino-1MQ: 12 units (200 mcg)
  Total each weekday: 42 units

Take in its own syringe Once per Week

• Retatrutide: Inject once weekly on your chosen day (e.g., every Sunday).

– Weeks 1-4: 20 units (1mg) per week

– Weeks 5–12: Increase to 40 units (2 mg) per week

– The Pantheon research protocol tops out at 2 mg per week in this cycle.

– Take on the same day and time each week for stable blood levels.

Weekends

• Skip BPC-157, TB-500, and 5-Amino-1MQ.
• Retatrutide is once weekly on your chosen day.

Cycle Length

• Total: 12 weeks
• BPC-157, TB-500, 5-Amino-1MQ: 5 days on / 2 days off
• Retatrutide: once weekly

Peptide Intake Overview

• BPC-157: 300 mcg × 60 weekdays = 18,000 mcg (18 mg)
• TB-500: 300 mcg × 60 weekdays = 18,000 mcg (18 mg)
• 5-Amino-1MQ: 200 mcg × 60 weekdays = 12,000 mcg (12 mg)
• Retatrutide: 1 mg × 4 weeks + 2 mg × 8 weeks = 20 mg total

Any supply left at the end of the cycle is custom math: use the online dosage calculator to work out the remaining doses for your vial size and schedule.

Inject Safely

Preferred sites (Subcutaneous)

• Abdomen, at least 5 cm from navel
• Outer thigh
• Upper-outer arm
  (Rotate 1 to 2 cm from last site)

Quick steps

• Clean the vial top with an alcohol pad
• Draw dose(s) into syringe
• Clean the location of injection with an alcohol pad
• Pinch and lift skin at the location of injection
• Inject slowly at a 45° angle just under the skin (SQ)
• Apply gentle pressure with alcohol pad for 30 seconds
• Dispose syringe in a sharps container

Notes

• Preferred sites: fatty part of abdomen (at least 5 cm from navel), outer thigh, or upper-outer arm
• Rotate injection site (1 to 2 cm)
• Wipe skin and let alcohol dry before injection
• If you miss a dose, resume at the next scheduled time. Do not double up
• Maintain hydration, movement, and good sleep
• Keep everything labeled and store safely
• Seek medical care urgently if you experience: spreading redness and warmth, severe swelling, fever, pus, red streaks, or signs of allergy (hives, facial swelling, trouble breathing)
• If you develop the flu, a significant infection, or any acute illness where your body’s ATP production needs to prioritize immune function, pause 5-Amino-1MQ and resume only once you have recovered.
• Do not use peptides if pregnant or breastfeeding.

Possible Side Effects (Common & Mild)

• Small bruise
• Brief redness or itch at site
• Occasional nausea or fatigue

Peptide Measurement Guide

• mg: milligram; measures the total amount of peptide in a vial
• mcg: microgram; measures an injection dose (1 mg = 1,000 mcg)
• mL: milliliter; measures the volume of BAC water for reconstitution
• unit: insulin-syringe marking for dose calculation (1 mL = 100 units on a standard insulin syringe)

Need Help Calculating Your Dose?

Our online dosage calculator makes it easy to prepare accurate peptide doses:

Helpful Guides

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Link: https://pantheonpeptides.com

Look up any Topic in our Help Center
Link: https://pantheonpeptides.com/ca/help

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References

1. Jastreboff AM, et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial. N Engl J Med. 2023;389(6):514-526. PubMed
2. Rosenstock J, et al. Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA. Lancet. 2023;402(10401):529-544. PubMed
3. Neelakantan H, et al. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice. Biochem Pharmacol. 2018;147:141-152. PubMed
4. Chang CH, et al. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. J Appl Physiol (1985). 2011;110(3):774-780. PubMed
5. Sikiric P, et al. Novel Cytoprotective Mediator, Stable Gastric Pentadecapeptide BPC 157. Vascular Recruitment and Gastrointestinal Tract Healing. Curr Pharm Des. 2018;24(18):1990-2001. PubMed
6. Goldstein AL, Kleinman HK. Advances in the basic and clinical applications of thymosin β4. Expert Opin Biol Ther. 2015;15 Suppl 1:S139-S145. PubMed

Disclaimer

This guide is for educational purposes only and is not medical advice. Peptides are research compounds and are not approved for human use unless prescribed by a medical practitioner. Always consult your medical practitioner before starting any protocol.