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Peptide Stacks & Cycles

CJC-1295 GHRP-2 2mg 5mg

Updated April 28, 2026


Primary Benefits

  • Stimulates natural growth hormone (GH) release and pulsatility
  • Promotes lean muscle development and fat metabolism
  • Supports tissue repair, skin rejuvenation, and recovery
  • May improve sleep, cognition, and circadian rhythm regulation
  • Enhances anti-aging and longevity pathways via increased IGF-1

Mechanism of Action

This stack pairs two powerful GH secretagogues with complementary mechanisms:

  • CJC-1295 without DAC is a modified form of GHRH that clears within about half an hour, which is why it is taken daily rather than weekly. Its short action is the point: it lifts a natural GH pulse rather than flooding the system.
  • GHRP-2 is a synthetic peptide that binds to ghrelin receptors, stimulating the pituitary to release GH. It works synergistically with CJC-1295 to amplify GH pulses, promoting muscle growth, fat loss, and regenerative activity without excessive appetite stimulation.

This stack is ideal for users who want the anabolic, fat-burning, and anti-aging benefits of increased GH levels—without using exogenous growth hormone.

Dosing & Protocol

Subcutaneous (SQ) Injection

Administer into the lower abdomen. Can be mixed in the same syringe after reconstitution.

CJC-1295 – 2mg Vial

  • Reconstitution: 2.0 mL bacteriostatic water
     (= 100 mcg per 10 units)
  • Daily Dose: 100–200 mcg (10–20 units)
  • Cycle:
     5 days on / 2 days off
     4–12 weeks
  • Timing: Take 2 hours after your last meal, just before bedtime

GHRP-2 – 5mg Vial

  • Reconstitution: 3.0 mL bacteriostatic water
     (= 166 mcg per 10 units)
  • Daily Dose: 166 mcg (10 units)
  • Cycle:
     5 days on / 2 days off
     6–12 weeks on, 2–4 weeks off
  • Timing: Based on personal preference; more ideal on an empty stomach (can be taken with CJC-1295 at bedtime)

Potential Side Effects

  • Mild injection site irritation
  • Temporary water retention
  • Increased hunger or fatigue (mild and temporary)
  • Rarely: tingling in extremities, flushing, or light-headedness
  • Not suitable for individuals with active cancer or uncontrolled diabetes

Who Is This Stack For?

  • Adults seeking body recomposition (lean muscle gain + fat reduction)
  • Athletes or biohackers recovering from injury or training fatigue
  • Individuals looking for anti-aging support via increased GH and IGF-1
  • People experiencing low GH symptoms: poor sleep, slow recovery, weight gain
  • Those who want natural GH support without using exogenous growth hormone

Notes

  • Always take on an empty stomach for best results (no food 1–2 hours before)
  • Store reconstituted peptides in the refrigerator and use within 45 days unless the product label/protocol says otherwise
  • Mix gently — avoid shaking vials
  • This stack works best when paired with exercise, fasting windows, or caloric control for enhanced GH response

References

  1. Teichman SL, et al. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006;91(3):799-805. PubMed
  2. Ionescu M, Frohman LA. Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. J Clin Endocrinol Metab. 2006;91(12):4792-4797. PubMed
  3. Jetté L, et al. Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog. Endocrinology. 2005;146(7):3052-3058. PubMed
  4. Laferrère B, et al. Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men. J Clin Endocrinol Metab. 2005;90(2):611-614. PubMed
  5. Arvat E, et al. Effects of GHRP-2 and hexarelin, two synthetic GH-releasing peptides, on GH, prolactin, ACTH and cortisol levels in man. Comparison with the effects of GHRH, TRH and hCRH. Peptides. 1997;18(6):885-891. PubMed

Disclaimer:
The information provided in this article is for educational and informational purposes only and is not intended as medical advice. These statements have not been evaluated by the FDA or Health Canada. Peptides and other compounds discussed are intended for research purposes only and are not approved for human consumption unless prescribed by a licensed medical professional. Always consult your healthcare provider before starting any new protocol, supplement, or treatment.