BPC-157 TB-500 5mg 5mg · Pantheon Help Center

Primary Benefits

Rapid healing of tendons, ligaments, and muscle tissue
Reduced localized and systemic inflammation
Enhanced angiogenesis and tissue remodeling
Support for post-surgical and chronic injury recovery
Potential relief from joint pain and stiffness
Improved mobility and functional rehabilitation outcomes

Mechanism of Action

This stack combines two of the most effective regenerative peptides:

BPC-157: Derived from a protective gastric protein, it promotes healing by modulating growth factors, supporting blood vessel formation (angiogenesis), and protecting tissues under cellular stress. It also supports gut health and neural repair.
TB-500: A synthetic form of thymosin beta-4, TB-500 enhances cellular migration, reduces inflammation, and accelerates soft tissue healing. It complements BPC-157 by deepening repair at the muscular and connective tissue level.

Together, they create a synergistic effect known as the “Wolverine Stack”, amplifying healing and regeneration throughout the body.

Dosing & Protocol

Subcutaneous (SQ) Injection:
Inject into the lower abdomen or near the injury site.

BPC-157 – 5mg Vial

Reconstitution: 2.5 mL bacteriostatic water
Daily Dose: 250–500 mcg (12.5–25 units)
Cycle: 5 days on / 2 days off
4–6 weeks (up to 6 months if needed)
Timing: Take in the morning on an empty stomach, at least 30 minutes before eating

TB-500 – 5mg Vial

Reconstitution: 2.5 mL bacteriostatic water
Daily Dose: 200–400 mcg (10–20 units)
Cycle: 5 days on / 2 days off
4 to 5 weeks
Timing: Take in the morning on an empty stomach, at least 30 minutes before eating

Note: These can be administered in the same syringe if mixed carefully after reconstitution.

Potential Side Effects

Mild injection site redness or irritation
Temporary fatigue or light-headedness
Rare reports of nausea (BPC-157)
No toxicity reported in animal studies to date; human safety data remain limited
Slight increase in appetite or energy in some users

Who Is This Stack For?

Individuals recovering from tendon, ligament, or muscle injuries
People recovering from surgery who want to support healing and reduce scar tissue
Athletes undergoing intense physical rehab or training
Those with joint pain, overuse injuries, or repetitive strain conditions
Biohackers seeking systemic repair and anti-inflammatory support

Notes

Store reconstituted peptides in the refrigerator and use within 45 days unless the product label or protocol says otherwise
Gently roll or swirl vials gently after reconstitution. Do not shake.
For enhanced results, consider combining with physical therapy or rehabilitation exercises
For gut-focused goals, inject the BPC-157 dose into the lower abdomen

References

Sikiric P, et al. Novel Cytoprotective Mediator, Stable Gastric Pentadecapeptide BPC 157. Vascular Recruitment and Gastrointestinal Tract Healing. Curr Pharm Des. 2018;24(18):1990-2001. PubMed
Seiwerth S, et al. BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing. Curr Pharm Des. 2018;24(18):1972-1989. PubMed
Gjurasin M, et al. Peptide therapy with pentadecapeptide BPC 157 in traumatic nerve injury. Regul Pept. 2010;160(1-3):33-41. PubMed
Malinda KM, et al. Thymosin beta4 accelerates wound healing. J Invest Dermatol. 1999;113(3):364-368. PubMed
Goldstein AL, et al. Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications. Expert Opin Biol Ther. 2012;12(1):37-51. PubMed

Disclaimer:
The information provided in this article is for educational and informational purposes only and is not intended as medical advice. These statements have not been evaluated by the FDA or Health Canada. Peptides and other compounds discussed are intended for research purposes only and are not approved for human consumption unless prescribed by a licensed medical professional. Always consult your healthcare provider before starting any new protocol, supplement, or treatment.