TB-500
Updated April 28, 2026
Primary Benefits:
- Accelerates healing of tendons, ligaments, and muscles
- Reduces inflammation (acute and chronic)
- Enhances flexibility and mobility
- Supports cardiovascular and endothelial tissue repair
- Promotes recovery after injury or surgery
Mechanism of Action:
TB-500 is a synthetic version of a naturally occurring peptide called thymosin beta-4. It promotes tissue regeneration by increasing cellular migration, modulating inflammation, and stimulating angiogenesis (new blood vessel formation). Its broad healing and anti-inflammatory effects make it useful in both injury recovery and performance optimization.
Dosing & Protocol:
Subcutaneous (SQ) Injection:
• Reconstitution:
– 2 mg vial → 2.0 ml bacteriostatic water
– 5 mg vial → 2.5 ml bacteriostatic water
• Daily Dose:
– 2 mg vial → 100–200 mcg (10–20 units)
– 5 mg vial → 200–400 mcg (10–20 units)
• Cycle:
5 days on / 2 days off
4 to 5 weeks
• Timing:
Take in the morning on an empty stomach, at least 30 minutes before eating
Potential Side Effects:
- Mild injection site irritation or redness
- Temporary fatigue or lethargy in some users
- Rarely, increased heart rate or light-headedness
- No toxicity reported in animal or early clinical studies
Common Stacks:
- With BPC-157: Popular “Wolverine Stack” for synergistic soft tissue regeneration
- With GHK-Cu: For wound repair and enhanced angiogenesis
- With CJC-1295/Ipamorelin: For growth hormone support alongside structural healing
Notes:
Inject subcutaneously into the lower abdomen or near injury site. Avoid shaking the vial—gently swirl after reconstitution. Store reconstituted peptide in the refrigerator between 2°C–8°C and use within 45 days unless the product label or protocol says otherwise. TB-500 works best when paired with physical therapy or post-surgical rehab protocols.
Disclaimer:
The information provided in this article is for educational and informational purposes only and is not intended as medical advice. These statements have not been evaluated by the FDA or Health Canada. Peptides and other compounds discussed are intended for research purposes only and are not approved for human consumption unless prescribed by a licensed medical professional. Always consult your healthcare provider before starting any new protocol, supplement, or treatment.